Proteomics Evaluation of Chemically Cleavable Activity-based Probes
نویسندگان
چکیده
منابع مشابه
Proteomics evaluation of chemically cleavable activity-based probes.
Activity-based probes (ABPs) that specifically target subsets of related enzymatic proteins are finding increasing use in proteomics research. One of the main applications for these reagents is affinity isolation of probe-labeled targets. However, the use of cheap and efficient biotin affinity tags on ABPs can be problematic due to difficulty in release of captured proteins. Here we describe th...
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ژورنال
عنوان ژورنال: Molecular & Cellular Proteomics
سال: 2007
ISSN: 1535-9476
DOI: 10.1074/mcp.m700124-mcp200